Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12070.154 | 0.9174 | 0.8492 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12070.154 | 0.9407 | 0.8919 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12070.154 | 0.9095 | 0.8347 | 1.1006 | |
| CAMA-1 | HR+ | Luminal | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12070.154 | 0.9284 | 0.8694 | 1.1006 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 12112.154 | 0.9294 | 0.9217 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 12112.154 | 0.8810 | 0.8664 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 12112.154 | 0.9791 | 0.9771 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 12112.154 | 0.9087 | 0.8981 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 12112.154 | 0.9541 | 0.9494 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 12112.154 | 0.9038 | 0.8925 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 12112.154 | 0.9872 | 0.9860 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 12112.154 | 0.8853 | 0.8713 | 1.8321 | |
| HCC1143 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 12112.154 | 0.9295 | 0.9218 | 1.8321 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10518.142 | 0.9187 | 0.8724 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10518.142 | 0.9750 | 0.9610 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10518.142 | 0.9711 | 0.9549 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0107 | uM | 10518.142 | 0.9815 | 0.9711 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0533 | uM | 10518.142 | 1.0529 | 1.0817 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.267 | uM | 10518.142 | 0.9299 | 0.8902 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 1.33 | uM | 10518.142 | 1.0064 | 1.0099 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 6.67 | uM | 10518.142 | 0.9579 | 0.9343 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 33.3 | uM | 10518.142 | 1.0011 | 1.0017 | 1.2869 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.0000853 | uM | 10753.154 | 1.0483 | 1.0664 | 1.4444 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.000427 | uM | 10753.154 | 1.0182 | 1.0251 | 1.4444 | |
| HCC1187 | TNBC | Basal A | FTase Inhibitor I | Ftase | MAPK | 0.00213 | uM | 10753.154 | 1.0069 | 1.0095 | 1.4444 |