Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7921.04 | 1.0240 | 1.0623 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7921.04 | 0.9739 | 0.9328 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7921.04 | 0.4900 | -0.2044 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7921.04 | 0.3062 | -0.5668 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7921.04 | 0.2660 | -0.6389 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7921.04 | 0.2679 | -0.6354 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7921.04 | 0.2312 | -0.6986 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7921.04 | 0.2941 | -0.5888 | 0.7738 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10146.049 | 1.0808 | 1.1832 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10146.049 | 1.2624 | 1.6017 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10146.049 | 1.1137 | 1.2585 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10146.049 | 0.2401 | -0.6004 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10146.049 | 0.1598 | -0.7475 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10146.049 | 0.1431 | -0.7771 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10146.049 | 0.1322 | -0.7961 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10146.049 | 0.1179 | -0.8210 | 0.8861 | |
| SUM185PE | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10146.049 | 0.0963 | -0.8575 | 0.8861 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9860.012 | 1.0050 | 1.0058 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9860.012 | 1.1073 | 1.1225 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9860.012 | 0.8077 | 0.7657 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9860.012 | 0.3353 | 0.0573 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9860.012 | 0.2269 | -0.1580 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9860.012 | 0.2415 | -0.1268 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9860.012 | 0.2310 | -0.1492 | 1.7144 | |
| SUM229PE | TNBC | - | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9860.012 | 0.2367 | -0.1370 | 1.7144 |