Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.032
uM
12206.161
 0.9355 0.8779 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.16
uM
12206.161
 0.9911 0.9831 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.8
uM
12206.161
 0.9477 0.9010 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
4
uM
12206.161
 0.9808 0.9638 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
20
uM
12206.161
 0.9947 0.9900 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
100
uM
12206.161
 0.8241 0.6658 1.0580
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.000256
uM
12594.166
 0.9922 0.9857 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.00128
uM
12594.166
 1.0011 1.0020 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.0064
uM
12594.166
 0.9734 0.9513 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.032
uM
12594.166
 0.9728 0.9501 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.16
uM
12594.166
 1.0219 1.0400 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.8
uM
12594.166
 1.0363 1.0663 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
4
uM
12594.166
 0.9680 0.9415 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
20
uM
12594.166
 0.9594 0.9257 1.0936
MDA-MB-157
TNBC
Basal B
 FR180204
ERK1/2
MAPK
100
uM
12594.166
 0.9414 0.8926 1.0936
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0000853
uM
10642.137
 0.9865 0.9591 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000427
uM
10642.137
 0.9983 0.9948 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00213
uM
10642.137
 0.9822 0.9461 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0107
uM
10642.137
 1.0129 1.0393 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0533
uM
10642.137
 0.9875 0.9621 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.267
uM
10642.137
 0.9752 0.9251 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
1.33
uM
10642.137
 1.0077 1.0235 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
6.67
uM
10642.137
 0.9599 0.8793 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
33.3
uM
10642.137
 0.8220 0.4840 0.6570
MDA-MB-175-VII
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0000853
uM
10818.149
 0.9789 0.9014 0.4210