Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.000427	uM	10818.149	0.9510	0.7749	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.00213	uM	10818.149	1.0011	1.0054	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0107	uM	10818.149	0.9700	0.8605	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0533	uM	10818.149	0.9687	0.8546	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.267	uM	10818.149	0.9859	0.9336	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	1.33	uM	10818.149	0.9917	0.9609	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	6.67	uM	10818.149	0.9347	0.7035	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	33.3	uM	10818.149	0.7590	0.0388	0.4210
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.000256	uM	12126.161	0.8858	0.6461	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.00128	uM	12126.161	0.8784	0.6240	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.0064	uM	12126.161	0.9055	0.7054	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.032	uM	12126.161	0.8697	0.5984	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.16	uM	12126.161	0.8934	0.6687	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	0.8	uM	12126.161	0.9481	0.8359	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	4	uM	12126.161	0.8721	0.6055	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	20	uM	12126.161	0.6754	0.0648	0.6227
MDA-MB-175-VII	HR+	Luminal	FR180204	ERK1/2	MAPK	100	uM	12126.161	0.2943	-0.7195	0.6227
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0000853	uM	10643.137	0.9659	0.8955	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.000427	uM	10643.137	1.0065	1.0200	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.00213	uM	10643.137	0.9952	0.9852	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0107	uM	10643.137	1.0226	1.0704	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.0533	uM	10643.137	1.0399	1.1248	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	0.267	uM	10643.137	1.0535	1.1679	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	1.33	uM	10643.137	1.0603	1.1896	0.6468
MDA-MB-361	HER2amp	Luminal	FR180204	ERK1/2	MAPK	6.67	uM	10643.137	0.9536	0.8584	0.6468

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)