Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF7
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.267
uM
10997.149
 1.0303 1.0479 1.2614
MCF7
HR+
Luminal
 FR180204
ERK1/2
MAPK
1.33
uM
10997.149
 0.9870 0.9793 1.2614
MCF7
HR+
Luminal
 FR180204
ERK1/2
MAPK
6.67
uM
10997.149
 0.9348 0.8960 1.2614
MCF7
HR+
Luminal
 FR180204
ERK1/2
MAPK
33.3
uM
10997.149
 0.9014 0.8421 1.2614
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0000853
uM
10519.137
 0.9672 0.9389 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000427
uM
10519.137
 0.9223 0.8554 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00213
uM
10519.137
 0.9302 0.8701 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0107
uM
10519.137
 0.9762 0.9557 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0533
uM
10519.137
 0.9915 0.9841 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.267
uM
10519.137
 0.9473 0.9020 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
1.33
uM
10519.137
 0.9698 0.9439 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
6.67
uM
10519.137
 0.9327 0.8748 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
33.3
uM
10519.137
 0.9429 0.8938 1.0772
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0000853
uM
10998.149
 0.9562 0.8875 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000427
uM
10998.149
 0.9598 0.8966 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00213
uM
10998.149
 0.9462 0.8619 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0107
uM
10998.149
 0.9851 0.9616 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0533
uM
10998.149
 1.0103 1.0266 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.267
uM
10998.149
 0.9618 0.9017 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
1.33
uM
10998.149
 1.0159 1.0412 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
6.67
uM
10998.149
 0.9568 0.8891 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
33.3
uM
10998.149
 1.0148 1.0384 0.7732
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000256
uM
12206.161
 0.9760 0.9547 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00128
uM
12206.161
 0.9274 0.8624 1.0580
MDA-MB-134-VI
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0064
uM
12206.161
 0.9626 0.9292 1.0580