Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10577.137 | 1.0431 | 1.0893 | 0.9653 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10577.137 | 0.9682 | 0.9341 | 0.9653 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10577.137 | 0.9990 | 0.9979 | 0.9653 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 10937.149 | 0.9352 | 0.9032 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 10937.149 | 1.0245 | 1.0361 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 10937.149 | 0.9912 | 0.9870 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 10937.149 | 0.9825 | 0.9741 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 10937.149 | 1.0084 | 1.0124 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 10937.149 | 0.9280 | 0.8925 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10937.149 | 1.0019 | 1.0028 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10937.149 | 0.9340 | 0.9016 | 1.3519 | |
| HCC3153 | TNBC | Basal A | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10937.149 | 1.0847 | 1.1240 | 1.3519 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 10578.137 | 0.9177 | 0.9081 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 10578.137 | 0.8660 | 0.8485 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 10578.137 | 0.9251 | 0.9165 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 10578.137 | 0.9573 | 0.9528 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 10578.137 | 0.9900 | 0.9891 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 10578.137 | 0.9064 | 0.8953 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 10578.137 | 0.9505 | 0.9452 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 10578.137 | 0.8918 | 0.8785 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 10578.137 | 0.8644 | 0.8466 | 1.8268 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 11850.161 | 0.9342 | 0.9355 | 2.0754 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 11850.161 | 0.9262 | 0.9274 | 2.0754 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 11850.161 | 0.9085 | 0.9097 | 2.0754 | |
| HCC38 | TNBC | Basal B | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 11850.161 | 0.9653 | 0.9663 | 2.0754 |