Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7477.074 | 1.1134 | 1.3703 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7477.074 | 1.0171 | 1.0544 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7477.074 | 0.6737 | 0.0710 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7477.074 | 0.9626 | 0.8829 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7477.074 | 0.8347 | 0.5030 | 0.6324 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.000853 | uM | 7482.074 | 0.8655 | 0.8430 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.00427 | uM | 7482.074 | 0.9228 | 0.9110 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.0213 | uM | 7482.074 | 0.9084 | 0.8942 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.107 | uM | 7482.074 | 0.8845 | 0.8657 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.533 | uM | 7482.074 | 0.2582 | -0.0709 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 2.67 | uM | 7482.074 | 0.2063 | -0.1816 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 13.3 | uM | 7482.074 | 0.1143 | -0.4142 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 66.7 | uM | 7482.074 | 0.0614 | -0.5881 | 1.7663 | |
| MB 157 | Unknown | Unknown | Etoposide | TOP2 | TOP | 333 | uM | 7482.074 | 0.0170 | -0.8009 | 1.7663 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7483.074 | 1.0867 | 1.0517 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7483.074 | 0.9931 | 0.9958 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7483.074 | 0.8748 | 0.9196 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7483.074 | 0.9710 | 0.9820 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7483.074 | 0.6740 | 0.7721 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7483.074 | 0.4844 | 0.6015 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7483.074 | 0.4083 | 0.5196 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7483.074 | 0.1547 | 0.1284 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7483.074 | 0.0829 | -0.0681 | 3.2613 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7484.074 | 1.0213 | 1.0162 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7484.074 | 0.9743 | 0.9802 | 2.6137 |