Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7473.074 | 0.1206 | -0.1315 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7473.074 | 0.0421 | -0.4265 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7473.074 | 0.0300 | -0.4978 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7474.074 | 1.2306 | 1.1647 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7474.074 | 1.2164 | 1.1551 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7474.074 | 1.1223 | 1.0900 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7474.074 | 1.3612 | 1.2496 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7474.074 | 1.0877 | 1.0652 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7474.074 | 0.8673 | 0.8943 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7474.074 | 0.1189 | -0.1124 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7474.074 | 0.0270 | -0.4955 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7474.074 | 0.0121 | -0.6288 | 2.6218 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7475.074 | 1.0310 | 1.0248 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7475.074 | 1.1635 | 1.1259 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7475.074 | 1.1406 | 1.1090 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7475.074 | 1.3012 | 1.2241 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7475.074 | 0.9822 | 0.9855 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7475.074 | 0.9133 | 0.9281 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7475.074 | 0.1592 | -0.0470 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7475.074 | 0.0771 | -0.2886 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7475.074 | 0.0036 | -0.7940 | 2.4793 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7477.074 | 0.8251 | 0.4757 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7477.074 | 1.2894 | 1.9893 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7477.074 | 1.0760 | 1.2455 | 0.6324 | |
| LY2 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7477.074 | 1.1262 | 1.4136 | 0.6324 |