Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7469.074 | 0.0475 | -0.5694 | 1.9843 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.000853 | uM | 7470.074 | 0.9551 | 0.9068 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.00427 | uM | 7470.074 | 0.9471 | 0.8902 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.0213 | uM | 7470.074 | 0.9640 | 0.9252 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.107 | uM | 7470.074 | 0.9304 | 0.8555 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 0.533 | uM | 7470.074 | 0.8538 | 0.6969 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 2.67 | uM | 7470.074 | 0.7813 | 0.5473 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 13.3 | uM | 7470.074 | 0.8014 | 0.5888 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 66.7 | uM | 7470.074 | 0.2435 | -0.5395 | 0.9618 | |
| HCC70 | TNBC | Basal A | Etoposide | TOP2 | TOP | 333 | uM | 7470.074 | 0.0898 | -0.8368 | 0.9618 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7472.074 | 1.2066 | 1.2504 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7472.074 | 0.9179 | 0.8953 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7472.074 | 0.9737 | 0.9668 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7472.074 | 1.3528 | 1.4180 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7472.074 | 1.8344 | 1.9277 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7472.074 | 1.4829 | 1.5615 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7472.074 | 0.5026 | 0.2983 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7472.074 | 0.0504 | -0.6937 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7472.074 | 0.0653 | -0.6398 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7473.074 | 1.0830 | 1.0639 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7473.074 | 1.0051 | 1.0040 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7473.074 | 1.0548 | 1.0425 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7473.074 | 1.6716 | 1.4491 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7473.074 | 1.2635 | 1.1932 | 2.5364 | |
| Hs 578T | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7473.074 | 0.9667 | 0.9735 | 2.5364 |