Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7484.074 | 0.9977 | 0.9983 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7484.074 | 0.8920 | 0.9144 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7484.074 | 0.7411 | 0.7834 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7484.074 | 0.7155 | 0.7596 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7484.074 | 0.5671 | 0.6098 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7484.074 | 0.2660 | 0.2050 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7484.074 | 0.2270 | 0.1342 | 2.6137 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7485.074 | 1.0210 | 1.0118 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7485.074 | 1.0030 | 1.0017 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7485.074 | 0.9761 | 0.9864 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7485.074 | 0.8818 | 0.9302 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7485.074 | 0.6535 | 0.7736 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7485.074 | 0.5281 | 0.6700 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7485.074 | 0.5148 | 0.6581 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7485.074 | 0.1536 | 0.1783 | 3.5413 | |
| MCF 10A | NM | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7485.074 | 0.0518 | -0.1329 | 3.5413 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 0.000853 | uM | 7487.074 | 0.9420 | 0.9176 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 0.00427 | uM | 7487.074 | 0.9562 | 0.9378 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 0.0213 | uM | 7487.074 | 0.9497 | 0.9286 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 0.107 | uM | 7487.074 | 0.8147 | 0.7312 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 0.533 | uM | 7487.074 | 0.6708 | 0.5097 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 2.67 | uM | 7487.074 | 0.5641 | 0.3363 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 13.3 | uM | 7487.074 | 0.5303 | 0.2793 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 66.7 | uM | 7487.074 | 0.4161 | 0.0784 | 1.4197 | |
| MCF 10F | NM | - | Etoposide | TOP2 | TOP | 333 | uM | 7487.074 | 0.3683 | -0.0104 | 1.4197 |