Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7824.017 | 0.7709 | 0.7114 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7824.017 | 0.3092 | -0.0098 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7824.017 | 0.3959 | 0.1482 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7824.017 | 0.3326 | 0.0343 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7824.017 | 0.0002 | -0.9871 | 1.6694 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7825.017 | 0.9705 | 0.9715 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7825.017 | 1.0064 | 1.0061 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7825.017 | 1.1040 | 1.0971 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7825.017 | 0.9612 | 0.9625 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7825.017 | 0.7557 | 0.7486 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7825.017 | 0.4679 | 0.3895 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7825.017 | 0.2808 | 0.0877 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7825.017 | 0.2886 | 0.1022 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7825.017 | 0.0005 | -0.9503 | 2.0855 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9347.017 | 1.0552 | 1.0673 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9347.017 | 0.9797 | 0.9749 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 9347.017 | 1.0624 | 1.0759 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9347.017 | 0.9526 | 0.9411 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 9347.017 | 0.8652 | 0.8294 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 9347.017 | 0.4649 | 0.2484 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 9347.017 | 0.3637 | 0.0733 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 9347.017 | 0.3549 | 0.0571 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 9347.017 | 0.0012 | -0.9683 | 1.6249 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7829.017 | 1.0326 | 1.0331 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7829.017 | 0.9952 | 0.9951 | 1.9566 |