Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 9933.034 | 0.0364 | -0.9945 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 9933.034 | 0.0432 | -0.9926 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 9933.034 | 0.0155 | -0.9988 | 0.5612 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7931.007 | 0.9820 | 0.9752 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7931.007 | 0.9502 | 0.9311 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7931.007 | 0.9551 | 0.9379 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7931.007 | 0.8437 | 0.7796 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7931.007 | 0.6917 | 0.5526 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7931.007 | 0.4714 | 0.1930 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7931.007 | 0.2728 | -0.1805 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7931.007 | 0.3623 | -0.0043 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7931.007 | 0.0703 | -0.6773 | 1.4557 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7932.043 | 1.0496 | 1.0994 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7932.043 | 0.9521 | 0.9039 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7932.043 | 0.9944 | 0.9888 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7932.043 | 0.9330 | 0.8658 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7932.043 | 0.7122 | 0.4235 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7932.043 | 0.4951 | -0.0111 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7932.043 | 0.2314 | -0.5385 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7932.043 | 0.4302 | -0.1410 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7932.043 | 0.1464 | -0.7083 | 0.9982 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9958.034 | 1.0098 | 1.0376 | 0.5217 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9958.034 | 0.9782 | 0.9174 | 0.5217 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9958.034 | 0.9826 | 0.9338 | 0.5217 | |
| ZR-75-1 | HR+ | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9958.034 | 0.8750 | 0.5483 | 0.5217 |