Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10150.034 | 0.0118 | -1.0000 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 10151.034 | 1.1086 | 1.7530 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 10151.034 | 0.9114 | 0.5000 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 10151.034 | 1.0680 | 1.4525 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 10151.034 | 0.9513 | 0.7131 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 10151.034 | 0.7534 | -0.1686 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 10151.034 | 0.4119 | -0.8721 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 10151.034 | 0.0948 | -0.9987 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 10151.034 | 0.0885 | -0.9989 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 10151.034 | 0.0097 | -1.0000 | 0.3226 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 10267.121 | 1.1315 | 1.6964 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 10267.121 | 1.0287 | 1.1419 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 10267.121 | 1.1219 | 1.6412 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 10267.121 | 0.9149 | 0.6129 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.147 | uM | 10267.121 | 0.7816 | 0.1020 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.736 | uM | 10267.121 | 0.4880 | -0.6472 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.68 | uM | 10267.121 | 0.1939 | -0.9622 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 18.4 | uM | 10267.121 | 0.2565 | -0.9255 | 0.4135 | |
| UACC-812 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 92 | uM | 10267.121 | 0.0483 | -0.9987 | 0.4135 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 9933.034 | 1.1997 | 1.7663 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 9933.034 | 0.9428 | 0.8007 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 9933.034 | 1.1873 | 1.7155 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 9933.034 | 1.0352 | 1.1271 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 9933.034 | 1.2285 | 1.8857 | 0.5612 | |
| UACC-893 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 9933.034 | 0.7266 | 0.1322 | 0.5612 |