Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 73.8 | uM | 7853.007 | 0.2391 | -0.3151 | 1.3351 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000189 | uM | 10056.034 | 1.0065 | 1.0151 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000945 | uM | 10056.034 | 1.0266 | 1.0617 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00472 | uM | 10056.034 | 1.0170 | 1.0393 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.0236 | uM | 10056.034 | 1.0502 | 1.1166 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.118 | uM | 10056.034 | 1.0195 | 1.0451 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.59 | uM | 10056.034 | 1.0275 | 1.0637 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 2.95 | uM | 10056.034 | 0.9434 | 0.8698 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 14.8 | uM | 10056.034 | 0.8260 | 0.6034 | 0.8648 | |
| HCC3153 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 73.8 | uM | 10056.034 | 0.2564 | -0.5855 | 0.8648 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9453.121 | 1.0128 | 1.0199 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9453.121 | 0.9795 | 0.9681 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9453.121 | 0.9972 | 0.9957 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9453.121 | 1.0039 | 1.0060 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.136 | uM | 9453.121 | 0.9867 | 0.9793 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.682 | uM | 9453.121 | 0.6894 | 0.4977 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 3.41 | uM | 9453.121 | 0.1833 | -0.4653 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 17.1 | uM | 9453.121 | 0.0600 | -0.7755 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 85.2 | uM | 9453.121 | 0.0349 | -0.8529 | 1.2860 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9469.121 | 1.0135 | 1.0239 | 1.1298 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9469.121 | 0.9706 | 0.9479 | 1.1298 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9469.121 | 1.0286 | 1.0505 | 1.1298 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9469.121 | 0.9976 | 0.9958 | 1.1298 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.136 | uM | 9469.121 | 0.9640 | 0.9362 | 1.1298 | |
| HCC38 | TNBC | Basal B | CPT-11 | TOP1 | TOP | 0.682 | uM | 9469.121 | 0.7495 | 0.5494 | 1.1298 |