Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MB 157	Unknown	Unknown	17-AAG	HSP90	HSP90	4	uM	9039.05	0.3919	-0.7753	0.4285
MB 157	Unknown	Unknown	17-AAG	HSP90	HSP90	20	uM	9039.05	0.2801	-0.8974	0.4285
MB 157	Unknown	Unknown	17-AAG	HSP90	HSP90	100	uM	9039.05	0.1951	-0.9559	0.4285
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.000256	uM	7867.04	0.9884	0.9905	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.00128	uM	7867.04	1.0555	1.0446	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.0064	uM	7867.04	0.9611	0.9678	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.032	uM	7867.04	0.7204	0.7490	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.16	uM	7867.04	0.0665	-0.3398	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.8	uM	7867.04	0.0612	-0.3616	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	4	uM	7867.04	0.0505	-0.4101	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	20	uM	7867.04	0.0423	-0.4513	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	100	uM	7867.04	0.0076	-0.7283	2.4460
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.000256	uM	7868.05	1.0710	1.0675	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.00128	uM	7868.05	1.0022	1.0021	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.0064	uM	7868.05	0.9912	0.9914	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.032	uM	7868.05	0.6606	0.6365	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.16	uM	7868.05	0.1189	-0.2862	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.8	uM	7868.05	0.1301	-0.2544	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	4	uM	7868.05	0.0949	-0.3597	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	20	uM	7868.05	0.0531	-0.5168	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	100	uM	7868.05	0.0112	-0.7725	2.0672
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.000256	uM	7870.037	0.9619	0.9659	2.2561
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.00128	uM	7870.037	0.9785	0.9808	2.2561
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.0064	uM	7870.037	0.9589	0.9632	2.2561
MCF 10A	NM	Basal B	17-AAG	HSP90	HSP90	0.032	uM	7870.037	0.7117	0.7201	2.2561

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)