Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7870.037 | 0.0982 | -0.2851 | 2.2561 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7870.037 | 0.0937 | -0.2998 | 2.2561 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7870.037 | 0.0715 | -0.3789 | 2.2561 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7870.037 | 0.0533 | -0.4548 | 2.2561 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7870.037 | 0.0313 | -0.5691 | 2.2561 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9551.037 | 0.9909 | 0.9930 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9551.037 | 1.0422 | 1.0318 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9551.037 | 0.9974 | 0.9980 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9551.037 | 0.6343 | 0.6810 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9551.037 | 0.0556 | -0.3360 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9551.037 | 0.0476 | -0.3745 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 9551.037 | 0.0441 | -0.3922 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 9551.037 | 0.0371 | -0.4313 | 2.6200 | |
| MCF 10A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 9551.037 | 0.0145 | -0.6021 | 2.6200 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7488.05 | 0.9821 | 0.9729 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7488.05 | 1.0772 | 1.1158 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7488.05 | 0.8753 | 0.8083 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7488.05 | 0.7140 | 0.5500 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7488.05 | 0.1340 | -0.5628 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7488.05 | 0.1043 | -0.6384 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 4 | uM | 7488.05 | 0.0974 | -0.6566 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 20 | uM | 7488.05 | 0.1007 | -0.6479 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 100 | uM | 7488.05 | 0.1053 | -0.6357 | 1.3218 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7871.05 | 0.9603 | 0.9381 | 1.2892 | |
| MCF 10F | NM | - | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7871.05 | 0.9844 | 0.9758 | 1.2892 |