Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7865.05 | 0.2814 | -0.1404 | 1.5015 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9536.037 | 0.9968 | 0.9953 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9536.037 | 1.0477 | 1.0699 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9536.037 | 1.0131 | 1.0193 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9536.037 | 0.9703 | 0.9561 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9536.037 | 0.5174 | 0.2306 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9536.037 | 0.2212 | -0.3422 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9536.037 | 0.2210 | -0.3427 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9536.037 | 0.2847 | -0.2078 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9536.037 | 0.0937 | -0.6509 | 1.3567 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10264.037 | 0.9790 | 0.9695 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10264.037 | 1.0699 | 1.0999 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10264.037 | 1.0069 | 1.0100 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10264.037 | 0.7934 | 0.6925 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10264.037 | 0.3418 | -0.0782 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10264.037 | 0.2933 | -0.1745 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 10264.037 | 0.2835 | -0.1944 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 10264.037 | 0.2631 | -0.2368 | 1.3861 | |
| LY2 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 10264.037 | 0.0882 | -0.6530 | 1.3861 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9039.05 | 0.9845 | 0.9286 | 0.4285 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9039.05 | 1.0404 | 1.1936 | 0.4285 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9039.05 | 0.9736 | 0.8791 | 0.4285 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9039.05 | 1.0638 | 1.3104 | 0.4285 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9039.05 | 0.8235 | 0.2713 | 0.4285 | |
| MB 157 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9039.05 | 0.4024 | -0.7611 | 0.4285 |