Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7917.13 | 0.7677 | 0.8176 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7917.13 | 0.5239 | 0.5830 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7917.13 | 0.0297 | -0.4396 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7917.13 | 0.0077 | -0.6555 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7917.13 | 0.0013 | -0.8198 | 2.7649 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9830.017 | 1.0757 | 1.0801 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9830.017 | 1.0806 | 1.0853 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9830.017 | 1.0719 | 1.0762 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9830.017 | 1.0215 | 1.0231 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9830.017 | 0.8819 | 0.8691 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9830.017 | 0.6396 | 0.5723 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9830.017 | 0.0742 | -0.5068 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9830.017 | 0.0015 | -0.9393 | 1.8576 | |
| SUM149PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9830.017 | 0.0038 | -0.9007 | 1.8576 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7918.017 | 0.7553 | 0.8312 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7918.017 | 0.9061 | 0.9390 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7918.017 | 0.8959 | 0.9321 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7918.017 | 0.7653 | 0.8388 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7918.017 | 0.8028 | 0.8666 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7918.017 | 0.4680 | 0.5756 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7918.017 | 0.1261 | 0.0436 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7918.017 | 0.0419 | -0.2616 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7918.017 | 0.0057 | -0.6044 | 3.1833 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7919.017 | 1.0993 | 1.0505 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7919.017 | 0.9752 | 0.9868 | 3.7958 |