Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13575.174 | 0.9654 | 0.9561 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13575.174 | 0.9743 | 0.9673 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13575.174 | 0.9864 | 0.9828 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13575.174 | 0.8878 | 0.8553 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13575.174 | 0.9850 | 0.9810 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13575.174 | 0.9277 | 0.9074 | 1.5845 | |
| 21NT | HER2amp | - | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13575.174 | 0.0776 | -0.6014 | 1.5845 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13091.174 | 0.9376 | 0.8447 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13091.174 | 0.9873 | 0.9681 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13091.174 | 0.9463 | 0.8661 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13091.174 | 0.9576 | 0.8940 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13091.174 | 0.9494 | 0.8738 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13091.174 | 0.2643 | -0.6236 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13091.174 | 0.5286 | -0.1016 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13091.174 | 0.2906 | -0.5761 | 0.7967 | |
| 600MPE | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13091.174 | 0.3629 | -0.4397 | 0.7967 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13030.174 | 1.0452 | 1.1052 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13030.174 | 0.9539 | 0.8934 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13030.174 | 1.0284 | 1.0660 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13030.174 | 1.0422 | 1.0982 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13030.174 | 0.9670 | 0.9237 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13030.174 | 0.4447 | -0.2193 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13030.174 | 0.4538 | -0.2005 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13030.174 | 0.7663 | 0.4683 | 0.8615 | |
| AU565 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13030.174 | 0.7143 | 0.3533 | 0.8615 |