Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7919.017 | 1.1087 | 1.0551 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7919.017 | 0.9997 | 0.9998 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7919.017 | 1.0175 | 1.0091 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7919.017 | 0.6466 | 0.7830 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7919.017 | 0.0622 | -0.0378 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7919.017 | 0.0168 | -0.3183 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7919.017 | 0.0033 | -0.5573 | 3.7958 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7920.13 | 0.9858 | 0.9935 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7920.13 | 0.9806 | 0.9911 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7920.13 | 0.9516 | 0.9775 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7920.13 | 0.9436 | 0.9737 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7920.13 | 0.9004 | 0.9528 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7920.13 | 0.7933 | 0.8974 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7920.13 | 0.1331 | 0.2640 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7920.13 | 0.0236 | -0.1473 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7920.13 | 0.0063 | -0.3684 | 4.3955 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9844.021 | 1.0736 | 1.0579 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9844.021 | 1.0071 | 1.0057 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9844.021 | 1.0936 | 1.0732 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9844.021 | 1.0017 | 1.0014 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9844.021 | 1.0122 | 1.0097 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9844.021 | 0.7973 | 0.8260 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9844.021 | 0.2195 | 0.0874 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9844.021 | 0.0628 | -0.3421 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9844.021 | 0.0155 | -0.6246 | 2.4889 |