Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 500 | uM | 9233.124 | 0.7316 | 0.4627 | 0.9990 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7811.018 | 1.0988 | 1.4447 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7811.018 | 0.9638 | 0.8487 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7811.018 | 1.0051 | 1.0217 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7811.018 | 0.8859 | 0.5451 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7811.018 | 0.8695 | 0.4848 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7811.018 | 0.8380 | 0.3725 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7811.018 | 0.8853 | 0.5429 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7811.018 | 0.4168 | -0.6902 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7811.018 | 0.0080 | -0.9999 | 0.4694 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9244.034 | 1.1443 | 1.4775 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 9244.034 | 0.9643 | 0.8879 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 9244.034 | 1.0244 | 1.0780 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 9244.034 | 0.8580 | 0.5680 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 9244.034 | 0.8681 | 0.5974 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 9244.034 | 0.9056 | 0.7083 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 9244.034 | 0.9362 | 0.8012 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 9244.034 | 1.0586 | 1.1893 | 0.6294 | ||
| HCC1187 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 9244.034 | 0.0135 | -0.9979 | 0.6294 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7813.018 | 1.2977 | 1.7254 | 0.8420 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7813.018 | 0.7597 | 0.4430 | 0.8420 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7813.018 | 0.8630 | 0.6789 | 0.8420 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7813.018 | 0.9291 | 0.8328 | 0.8420 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7813.018 | 0.9339 | 0.8439 | 0.8420 | ||
| HCC1395 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7813.018 | 0.7928 | 0.5179 | 0.8420 |