Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9972.125 | 0.9749 | 0.9575 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9972.125 | 1.0090 | 1.0151 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9972.125 | 1.0134 | 1.0226 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9972.125 | 1.0282 | 1.0474 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9972.125 | 0.9796 | 0.9655 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9972.125 | 0.9760 | 0.9595 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9972.125 | 0.9886 | 0.9807 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9972.125 | 0.9172 | 0.8594 | 1.1854 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9997.026 | 1.1225 | 1.2144 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9997.026 | 1.0393 | 1.0691 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9997.026 | 1.0623 | 1.1094 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9997.026 | 1.0340 | 1.0598 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9997.026 | 1.0230 | 1.0405 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9997.026 | 1.0008 | 1.0014 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9997.026 | 1.0094 | 1.0166 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9997.026 | 1.0400 | 1.0702 | 1.1348 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9997.026 | 0.9761 | 0.9578 | 1.1348 | |
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7787.018 | 1.1183 | 1.6859 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7787.018 | 0.9303 | 0.6532 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7787.018 | 0.9413 | 0.7050 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7787.018 | 1.0535 | 1.2944 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 8 | uM | 7787.018 | 1.0429 | 1.2345 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 40 | uM | 7787.018 | 0.9781 | 0.8865 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 200 | uM | 7787.018 | 1.0263 | 1.1417 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1000 | uM | 7787.018 | 0.8826 | 0.4387 | 0.3791 |