Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9045.018 | 1.0864 | 1.1593 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9045.018 | 0.9948 | 0.9905 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9045.018 | 1.0353 | 1.0652 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9045.018 | 0.9320 | 0.8738 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9045.018 | 1.1574 | 1.2897 | 1.0807 | |
| UACC-893 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9045.018 | 1.1831 | 1.3366 | 1.0807 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7931.042 | 1.0727 | 1.1038 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7931.042 | 1.0913 | 1.1300 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7931.042 | 1.0519 | 1.0743 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7931.042 | 1.0563 | 1.0806 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7931.042 | 1.0767 | 1.1093 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7931.042 | 1.0407 | 1.0583 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7931.042 | 0.9985 | 0.9979 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7931.042 | 0.8825 | 0.8278 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7931.042 | 0.9836 | 0.9763 | 1.3878 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7932.052 | 1.0417 | 1.0941 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7932.052 | 1.1087 | 1.2465 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7932.052 | 1.0677 | 1.1532 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7932.052 | 1.0480 | 1.1084 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7932.052 | 1.0578 | 1.1307 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7932.052 | 1.0627 | 1.1417 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7932.052 | 0.9935 | 0.9852 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7932.052 | 1.0646 | 1.1461 | 0.8877 | |
| ZR-75-1 | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7932.052 | 1.0262 | 1.0592 | 0.8877 | |
| ZR75B | HR+ | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9972.125 | 1.0163 | 1.0275 | 1.1854 |