Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9797.011 | 1.0852 | 1.3551 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9797.011 | 1.0235 | 1.0951 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9797.011 | 0.9422 | 0.7755 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9797.011 | 0.6225 | -0.2246 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9797.011 | 0.0408 | -0.9967 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9797.011 | 0.0116 | -0.9997 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10139.021 | 0.9898 | 0.9756 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10139.021 | 1.0331 | 1.0791 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10139.021 | 0.9941 | 0.9860 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10139.021 | 1.0394 | 1.0943 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10139.021 | 0.9913 | 0.9793 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10139.021 | 0.9285 | 0.8308 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10139.021 | 0.6373 | 0.1689 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10139.021 | 0.0564 | -0.9350 | 0.8389 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10139.021 | 0.0165 | -0.9850 | 0.8389 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7917.075 | 0.9422 | 0.9613 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7917.075 | 1.0163 | 1.0106 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7917.075 | 0.9488 | 0.9658 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7917.075 | 1.0186 | 1.0122 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7917.075 | 0.8613 | 0.9044 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7917.075 | 0.7019 | 0.7807 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7917.075 | 0.1622 | 0.1012 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7917.075 | 0.0048 | -0.6530 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7917.075 | 0.0016 | -0.7567 | 3.0479 | |
| SUM149PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9830.011 | 0.9562 | 0.9574 | 2.0792 |