Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7912.018 | 0.9996 | 0.9988 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7912.018 | 0.9671 | 0.9092 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7912.018 | 0.6235 | 0.0380 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7912.018 | 0.9020 | 0.7332 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7912.018 | 0.8263 | 0.5347 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7912.018 | 0.7992 | 0.4652 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7912.018 | 0.5970 | -0.0227 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7912.018 | 0.5447 | -0.1394 | 0.7203 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9759.006 | 1.0336 | 1.0527 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9759.006 | 1.0220 | 1.0345 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9759.006 | 0.5500 | 0.2496 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9759.006 | 0.8686 | 0.7902 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9759.006 | 0.8858 | 0.8180 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9759.006 | 0.8641 | 0.7830 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9759.006 | 0.8838 | 0.8148 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9759.006 | 0.8097 | 0.6940 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9759.006 | 0.7365 | 0.5724 | 1.2714 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9760.026 | 1.0323 | 1.0602 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9760.026 | 0.9953 | 0.9912 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9760.026 | 0.9274 | 0.8642 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9760.026 | 0.8415 | 0.7026 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9760.026 | 0.8799 | 0.7752 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9760.026 | 0.8643 | 0.7457 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9760.026 | 0.8774 | 0.7704 | 1.0724 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9760.026 | 0.7956 | 0.6159 | 1.0724 |