Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9759.011 | 0.6639 | 0.4278 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9759.011 | 0.2254 | -0.4130 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9759.011 | 0.0297 | -0.8893 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9759.011 | 0.0628 | -0.7950 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9760.011 | 1.0317 | 1.0658 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9760.011 | 1.1011 | 1.2102 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9760.011 | 0.9573 | 0.9114 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9760.011 | 1.1314 | 1.2735 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9760.011 | 1.1194 | 1.2485 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9760.011 | 0.8822 | 0.7559 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9760.011 | 0.1806 | -0.6615 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9760.011 | 0.0467 | -0.9168 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9760.011 | 0.0247 | -0.9570 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10127.12 | 0.9853 | 0.9426 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10127.12 | 1.1143 | 1.4752 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10127.12 | 1.0842 | 1.3454 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10127.12 | 1.1278 | 1.5349 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10127.12 | 1.0800 | 1.3272 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10127.12 | 0.7528 | 0.1431 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10127.12 | 0.1173 | -0.9706 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10127.12 | 0.1164 | -0.9711 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10127.12 | 0.0187 | -0.9992 | 0.5076 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9797.011 | 1.0373 | 1.1517 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9797.011 | 1.0304 | 1.1236 | 0.5004 | |
| SUM1315MO2 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9797.011 | 0.9663 | 0.8674 | 0.5004 |