Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7905.018 | 0.4843 | -0.1074 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7905.018 | 0.5405 | 0.0086 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7905.018 | 0.4269 | -0.2242 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7905.018 | 0.4311 | -0.2158 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7905.018 | 0.1008 | -0.8443 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7905.018 | 0.0088 | -0.9896 | 0.8988 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7906.018 | 0.6093 | 0.1594 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7906.018 | 0.4209 | -0.2283 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7906.018 | 0.8744 | 0.7253 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7906.018 | 0.5676 | 0.0723 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7906.018 | 0.5007 | -0.0659 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7906.018 | 0.5475 | 0.0308 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7906.018 | 0.3283 | -0.4130 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7906.018 | 0.1345 | -0.7802 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7906.018 | 0.0424 | -0.9383 | 0.9087 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7907.018 | 1.0702 | 1.0912 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 7907.018 | 0.8101 | 0.7416 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 7907.018 | 0.6337 | 0.4820 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 7907.018 | 0.4459 | 0.1763 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 7907.018 | 0.5115 | 0.2873 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 7907.018 | 0.4128 | 0.1182 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 7907.018 | 0.4489 | 0.1814 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 7907.018 | 0.2923 | -0.1087 | 1.5217 | ||
| MDA-MB-468 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 5000 | uM | 7907.018 | 0.0232 | -0.8313 | 1.5217 | ||
| SK-BR-3 | HER2amp | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7912.018 | 0.9866 | 0.9628 | 0.7203 |