Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7875.011 | 0.9418 | 0.9306 | 1.6960 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7875.011 | 0.8052 | 0.7601 | 1.6960 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7875.011 | 0.3786 | 0.1280 | 1.6960 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7875.011 | 0.0994 | -0.4874 | 1.6960 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9583.011 | 1.0511 | 1.0979 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9583.011 | 0.9901 | 0.9810 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9583.011 | 1.0785 | 1.1504 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9583.011 | 0.9810 | 0.9635 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9583.011 | 1.0212 | 1.0406 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9583.011 | 0.9789 | 0.9594 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9583.011 | 0.9150 | 0.8367 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9583.011 | 0.7163 | 0.4521 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9583.011 | 0.3177 | -0.3344 | 1.0421 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10073.021 | 0.9833 | 0.9413 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10073.021 | 1.0527 | 1.1898 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10073.021 | 0.9935 | 0.9770 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10073.021 | 1.0250 | 1.0890 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10073.021 | 1.0255 | 1.0908 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10073.021 | 1.0203 | 1.0721 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10073.021 | 0.9861 | 0.9512 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10073.021 | 0.8503 | 0.5020 | 0.5665 | |
| MCF7 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10073.021 | 0.4535 | -0.5048 | 0.5665 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10077.119 | 0.9867 | 0.9509 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10077.119 | 1.1287 | 1.5057 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10077.119 | 0.9930 | 0.9738 | 0.5371 |