Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10077.119 | 1.0562 | 1.2144 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10077.119 | 1.1161 | 1.4539 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10077.119 | 1.0758 | 1.2916 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10077.119 | 1.0388 | 1.1467 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10077.119 | 0.6146 | -0.1921 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10077.119 | 0.0821 | -0.9810 | 0.5371 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10265.021 | 0.9583 | 0.7431 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10265.021 | 1.1959 | 2.5650 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10265.021 | 0.9777 | 0.8593 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10265.021 | 1.0657 | 1.4567 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10265.021 | 1.0812 | 1.5734 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10265.021 | 1.0582 | 1.4014 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10265.021 | 0.9843 | 0.9006 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10265.021 | 0.8944 | 0.3948 | 0.3095 | |
| MDA-MB-134-VI | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10265.021 | 0.0867 | -0.9993 | 0.3095 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10093.021 | 0.9343 | 0.8571 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10093.021 | 0.8554 | 0.6868 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10093.021 | 0.8207 | 0.6124 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10093.021 | 0.9766 | 0.9490 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10093.021 | 0.8905 | 0.7625 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10093.021 | 0.9126 | 0.8102 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10093.021 | 0.6816 | 0.3169 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10093.021 | 0.3332 | -0.3965 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10093.021 | 0.0049 | -0.9939 | 0.9172 | |
| MDA-MB-175-VII | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7885.011 | 1.0182 | 1.0721 | 0.5102 |