Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9421.021 | 0.9155 | 0.5782 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9421.021 | 0.5956 | -0.5023 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9421.021 | 0.2365 | -0.9582 | 0.3726 | |
| HCC2185 | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9421.021 | 0.0148 | -1.0000 | 0.3726 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7853.011 | 0.9947 | 0.9935 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7853.011 | 1.0186 | 1.0227 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7853.011 | 1.0643 | 1.0778 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7853.011 | 0.9835 | 0.9797 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7853.011 | 0.9789 | 0.9741 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7853.011 | 0.9515 | 0.9401 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7853.011 | 0.4602 | 0.2434 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7853.011 | 0.0831 | -0.5641 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7853.011 | 0.1905 | -0.2756 | 1.6331 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10056.021 | 0.9565 | 0.9019 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10056.021 | 0.9852 | 0.9666 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10056.021 | 0.9666 | 0.9246 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10056.021 | 0.9615 | 0.9132 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10056.021 | 0.9681 | 0.9279 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10056.021 | 0.9296 | 0.8415 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10056.021 | 0.6336 | 0.1934 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10056.021 | 0.0956 | -0.8595 | 0.8839 | |
| HCC3153 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10056.021 | 0.2593 | -0.5657 | 0.8839 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9028.075 | 1.0831 | 1.2840 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9028.075 | 1.0364 | 1.1226 | 0.6011 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9028.075 | 0.9767 | 0.9229 | 0.6011 |