Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7874.018 | 1.0640 | 1.0766 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7874.018 | 0.9963 | 0.9955 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7874.018 | 0.7268 | 0.6484 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7874.018 | 0.5901 | 0.4529 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7874.018 | 0.6678 | 0.5660 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7874.018 | 0.7299 | 0.6527 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7874.018 | 0.6482 | 0.5380 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7874.018 | 0.0776 | -0.5749 | 1.6506 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7875.018 | 0.9910 | 0.9891 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 7875.018 | 0.9735 | 0.9679 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 7875.018 | 0.9399 | 0.9265 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 7875.018 | 0.8343 | 0.7928 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 7875.018 | 0.8032 | 0.7521 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 7875.018 | 0.7333 | 0.6584 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 7875.018 | 0.5927 | 0.4585 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7875.018 | 0.3698 | 0.0970 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7875.018 | 0.0484 | -0.6784 | 1.6565 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9583.026 | 1.0036 | 1.0057 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9583.026 | 0.9834 | 0.9739 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9583.026 | 0.9666 | 0.9473 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9583.026 | 0.9065 | 0.8516 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9583.026 | 0.8115 | 0.6974 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9583.026 | 0.8005 | 0.6793 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9583.026 | 0.8049 | 0.6866 | 1.2731 | ||
| MCF7 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9583.026 | 0.8126 | 0.6991 | 1.2731 |