Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7449.074 | 1.0547 | 1.0531 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7449.074 | 0.3282 | 0.1559 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7449.074 | 0.3282 | 0.1559 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7449.074 | 0.0349 | -0.6164 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7449.074 | 0.0349 | -0.6164 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7449.074 | 0.0314 | -0.6361 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7449.074 | 0.0314 | -0.6361 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7449.074 | 0.0325 | -0.6296 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7449.074 | 0.0325 | -0.6296 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7449.074 | 0.0445 | -0.5677 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7449.074 | 0.0445 | -0.5677 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7449.074 | 0.0730 | -0.4482 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7449.074 | 0.0730 | -0.4482 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14727.203 | 0.9785 | 0.9757 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14727.203 | 0.9785 | 0.9757 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14727.203 | 0.8303 | 0.8014 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14727.203 | 0.8303 | 0.8014 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14727.203 | 0.6783 | 0.6079 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14727.203 | 0.6783 | 0.6079 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14727.203 | 0.1412 | -0.3346 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14727.203 | 0.1412 | -0.3346 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14727.203 | 0.0789 | -0.5203 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14727.203 | 0.0789 | -0.5203 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14727.203 | 0.0959 | -0.4648 | 1.7785 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14727.203 | 0.0959 | -0.4648 | 1.7785 |