Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7447.074 | 0.0741 | -0.6306 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7447.074 | 0.0741 | -0.6306 | 1.5411 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7448.074 | 1.0061 | 1.0042 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7448.074 | 1.0061 | 1.0042 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7448.074 | 0.9781 | 0.9847 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7448.074 | 0.9781 | 0.9847 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7448.074 | 0.9623 | 0.9736 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7448.074 | 0.9623 | 0.9736 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7448.074 | 0.3031 | 0.3219 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7448.074 | 0.3031 | 0.3219 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7448.074 | 0.0431 | -0.3281 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7448.074 | 0.0431 | -0.3281 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7448.074 | 0.0319 | -0.3948 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7448.074 | 0.0319 | -0.3948 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7448.074 | 0.0393 | -0.3495 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7448.074 | 0.0393 | -0.3495 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7448.074 | 0.0512 | -0.2866 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7448.074 | 0.0512 | -0.2866 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7448.074 | 0.0668 | -0.2178 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7448.074 | 0.0668 | -0.2178 | 2.8830 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7449.074 | 1.0528 | 1.0513 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7449.074 | 1.0528 | 1.0513 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7449.074 | 0.9894 | 0.9896 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7449.074 | 0.9894 | 0.9896 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7449.074 | 1.0547 | 1.0531 | 2.0321 |