Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7431.074 | 0.9545 | 0.9361 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7431.074 | 0.9545 | 0.9361 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7431.074 | 0.9617 | 0.9463 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7431.074 | 0.9617 | 0.9463 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7431.074 | 0.9773 | 0.9682 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7431.074 | 0.9773 | 0.9682 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7431.074 | 0.2891 | -0.1578 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7431.074 | 0.2891 | -0.1578 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7431.074 | 0.0096 | -0.9213 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7431.074 | 0.0096 | -0.9213 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7431.074 | 0.0058 | -0.9450 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7431.074 | 0.0058 | -0.9450 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7431.074 | 0.0073 | -0.9351 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7431.074 | 0.0073 | -0.9351 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7431.074 | 0.0076 | -0.9332 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7431.074 | 0.0076 | -0.9332 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7431.074 | 0.0071 | -0.9365 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7431.074 | 0.0071 | -0.9365 | 1.4349 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7432.074 | 1.0544 | 1.1272 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7432.074 | 1.0544 | 1.1272 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7432.074 | 1.0467 | 1.1091 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7432.074 | 1.0467 | 1.1091 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7432.074 | 0.9172 | 0.8087 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7432.074 | 0.9172 | 0.8087 | 0.8598 | |
| HCC1187 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7432.074 | 0.0819 | -0.8911 | 0.8598 |