Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15272.203 | 0.9517 | 0.9496 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15272.203 | 0.9517 | 0.9496 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15272.203 | 1.0210 | 1.0216 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15272.203 | 1.0210 | 1.0216 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15272.203 | 0.6036 | 0.5420 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15272.203 | 0.6036 | 0.5420 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15272.203 | 0.0613 | -0.5254 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15272.203 | 0.0613 | -0.5254 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15272.203 | 0.0202 | -0.7317 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15272.203 | 0.0202 | -0.7317 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15272.203 | 0.0149 | -0.7711 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15272.203 | 0.0149 | -0.7711 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15272.203 | 0.0145 | -0.7744 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15272.203 | 0.0145 | -0.7744 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15272.203 | 0.0149 | -0.7708 | 1.9412 | |
| CAL-120 | TNBC | Luminal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15272.203 | 0.0149 | -0.7708 | 1.9412 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15276.203 | 0.9667 | 0.9602 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15276.203 | 0.9667 | 0.9602 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15276.203 | 0.9041 | 0.8837 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15276.203 | 0.9041 | 0.8837 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15276.203 | 0.9417 | 0.9298 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15276.203 | 0.9417 | 0.9298 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15276.203 | 0.8132 | 0.7688 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15276.203 | 0.8132 | 0.7688 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15276.203 | 0.3220 | 0.0200 | 1.6831 |