Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11855.158 | 0.9899 | 0.9708 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11855.158 | 0.9111 | 0.7488 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11855.158 | 0.9909 | 0.9739 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11855.158 | 0.9012 | 0.7218 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 11855.158 | 0.8933 | 0.6998 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 11855.158 | 0.9030 | 0.7265 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 11855.158 | 0.8220 | 0.5079 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 11855.158 | 0.8523 | 0.5886 | 0.6941 | |
| BT-483 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 11855.158 | 0.8246 | 0.5149 | 0.6941 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12305.165 | 0.9563 | 0.9672 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12305.165 | 0.9536 | 0.9651 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12305.165 | 0.9480 | 0.9609 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0107 | uM | 12305.165 | 0.9727 | 0.9796 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0533 | uM | 12305.165 | 0.9482 | 0.9610 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.267 | uM | 12305.165 | 0.9896 | 0.9923 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 1.33 | uM | 12305.165 | 0.9224 | 0.9411 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 12305.165 | 0.9083 | 0.9300 | 2.7020 | |
| BT-549 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 33.3 | uM | 12305.165 | 0.6816 | 0.7355 | 2.7020 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 10473.141 | 1.0189 | 1.0295 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 10473.141 | 0.9454 | 0.9142 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 10473.141 | 0.9732 | 0.9580 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 10473.141 | 0.9732 | 0.9580 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 10473.141 | 1.0179 | 1.0279 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 10473.141 | 0.9104 | 0.8586 | 1.2804 | |
| CAMA-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 10473.141 | 0.9490 | 0.9198 | 1.2804 |