Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7917.016 | 1.0037 | 1.0025 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7917.016 | 0.9005 | 0.9303 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7917.016 | 0.7497 | 0.8141 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7917.016 | 0.6152 | 0.6966 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7917.016 | 0.5892 | 0.6720 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7917.016 | 0.1695 | 0.0964 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7917.016 | 0.0086 | -0.6003 | 2.9532 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 9830.019 | 1.0926 | 1.0951 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 9830.019 | 0.9601 | 0.9577 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 9830.019 | 1.0116 | 1.0122 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 9830.019 | 0.9360 | 0.9318 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 9830.019 | 0.7028 | 0.6620 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 9830.019 | 0.6136 | 0.5477 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 9830.019 | 0.6178 | 0.5533 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 9830.019 | 0.6215 | 0.5582 | 1.9053 | |
| SUM149PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 9830.019 | 0.5002 | 0.3903 | 1.9053 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7918.016 | 1.0401 | 1.0254 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7918.016 | 0.8862 | 0.9240 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7918.016 | 0.9439 | 0.9633 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7918.016 | 0.7075 | 0.7900 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7918.016 | 1.0416 | 1.0263 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7918.016 | 0.7660 | 0.8362 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7918.016 | 0.5806 | 0.6801 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7918.016 | 0.9966 | 0.9978 | 3.1190 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7918.016 | 0.5833 | 0.6825 | 3.1190 |