Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7919.016 | 1.0010 | 1.0006 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7919.016 | 0.9658 | 0.9805 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7919.016 | 0.9904 | 0.9945 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7919.016 | 0.9181 | 0.9525 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7919.016 | 0.8982 | 0.9404 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7919.016 | 0.9337 | 0.9617 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7919.016 | 0.7049 | 0.8123 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7919.016 | 0.3932 | 0.5376 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7919.016 | 0.0105 | -0.4465 | 3.5497 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7920.016 | 1.1426 | 1.0626 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7920.016 | 1.0711 | 1.0320 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7920.016 | 1.0267 | 1.0122 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7920.016 | 1.0011 | 1.0005 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7920.016 | 0.9965 | 0.9984 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7920.016 | 0.9315 | 0.9675 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7920.016 | 0.8698 | 0.9365 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7920.016 | 0.1866 | 0.3563 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7920.016 | 0.0168 | -0.2225 | 4.3230 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 9042.016 | 1.0028 | 1.0020 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 9042.016 | 0.9372 | 0.9550 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 9042.016 | 1.0562 | 1.0387 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 9042.016 | 0.8617 | 0.8983 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 9042.016 | 0.9007 | 0.9280 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 9042.016 | 0.9344 | 0.9530 | 2.8524 | |
| SUM159PT | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 9042.016 | 0.8368 | 0.8789 | 2.8524 |