Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7903.016 | 1.0012 | 1.0022 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7903.016 | 0.9991 | 0.9984 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7903.016 | 1.0194 | 1.0347 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7903.016 | 0.9890 | 0.9803 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7903.016 | 1.0444 | 1.0791 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7903.016 | 0.8935 | 0.8087 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7903.016 | 1.0083 | 1.0147 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7903.016 | 0.7985 | 0.6359 | 1.1196 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9708.019 | 1.0449 | 1.0773 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9708.019 | 1.0108 | 1.0187 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9708.019 | 1.1016 | 1.1742 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9708.019 | 0.9632 | 0.9363 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9708.019 | 0.9768 | 0.9599 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9708.019 | 0.9473 | 0.9087 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9708.019 | 0.8801 | 0.7912 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9708.019 | 1.0067 | 1.0115 | 1.1580 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9708.019 | 0.7966 | 0.6433 | 1.1580 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7905.016 | 1.0228 | 1.0737 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7905.016 | 0.8935 | 0.6699 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7905.016 | 0.9358 | 0.7983 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7905.016 | 0.8814 | 0.6338 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7905.016 | 1.2252 | 1.7696 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7905.016 | 1.1885 | 1.6378 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7905.016 | 1.1624 | 1.5456 | 0.6240 | |
| MDA-MB-468 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7905.016 | 1.3116 | 2.0891 | 0.6240 |