Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7897.016 | 1.0187 | 1.0515 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7897.016 | 1.0376 | 1.1039 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7897.016 | 1.0406 | 1.1120 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7897.016 | 0.9568 | 0.8826 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7897.016 | 1.0062 | 1.0170 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7897.016 | 0.9146 | 0.7698 | 0.7300 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7898.016 | 1.0382 | 1.0628 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7898.016 | 0.9327 | 0.8883 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7898.016 | 1.0625 | 1.1024 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7898.016 | 0.8819 | 0.8031 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7898.016 | 0.9893 | 0.9824 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7898.016 | 1.0172 | 1.0283 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7898.016 | 1.0188 | 1.0309 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7898.016 | 1.0974 | 1.1593 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7898.016 | 0.8730 | 0.7881 | 1.2127 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7902.016 | 1.0988 | 1.1016 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7902.016 | 0.6962 | 0.6530 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7902.016 | 1.1115 | 1.1144 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7902.016 | 0.7575 | 0.7280 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7902.016 | 0.9977 | 0.9976 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7902.016 | 0.8714 | 0.8603 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7902.016 | 1.1096 | 1.1125 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7902.016 | 0.8062 | 0.7857 | 1.9004 | |
| MDA-MB-436 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7902.016 | 0.2760 | 0.0159 | 1.9004 | |
| MDA-MB-453 | TNBC | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7903.016 | 0.9981 | 0.9967 | 1.1196 |