Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7894.016 | 0.9423 | 0.8524 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7894.016 | 0.7642 | 0.4138 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7894.016 | 0.8154 | 0.5372 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7894.016 | 0.4194 | -0.3479 | 0.7753 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7895.016 | 0.9632 | 0.9431 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7895.016 | 1.0042 | 1.0065 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7895.016 | 0.9897 | 0.9841 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7895.016 | 0.9717 | 0.9563 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7895.016 | 0.9975 | 0.9961 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7895.016 | 0.9502 | 0.9227 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7895.016 | 0.7658 | 0.6282 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7895.016 | 0.5338 | 0.2330 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7895.016 | 0.0831 | -0.7058 | 1.2977 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7896.016 | 0.9876 | 0.9721 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7896.016 | 0.9954 | 0.9898 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7896.016 | 0.9983 | 0.9961 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7896.016 | 0.9984 | 0.9964 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7896.016 | 0.9897 | 0.9769 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7896.016 | 0.9471 | 0.8817 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7896.016 | 0.7112 | 0.3644 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7896.016 | 0.8104 | 0.5796 | 0.8912 | |
| MDA-MB-361 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7896.016 | 0.6542 | 0.2423 | 0.8912 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7897.016 | 1.0134 | 1.0367 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7897.016 | 0.9635 | 0.9007 | 0.7300 | |
| MDA-MB-415 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7897.016 | 0.9320 | 0.8162 | 0.7300 |