Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15288.203 | 0.1081 | -0.8815 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15288.203 | 0.1081 | -0.8815 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15288.203 | 0.0500 | -0.9554 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15288.203 | 0.0500 | -0.9554 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15288.203 | 0.0237 | -0.9828 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15288.203 | 0.0237 | -0.9828 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15288.203 | 0.0250 | -0.9815 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15288.203 | 0.0250 | -0.9815 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15288.203 | 0.0225 | -0.9838 | 0.7873 | |
| EFM-192B | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15288.203 | 0.0225 | -0.9838 | 0.7873 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15292.203 | 0.9948 | 0.9932 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15292.203 | 0.9948 | 0.9932 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15292.203 | 0.7668 | 0.6836 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15292.203 | 0.7668 | 0.6836 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15292.203 | 0.6840 | 0.5632 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15292.203 | 0.6840 | 0.5632 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15292.203 | 0.3815 | 0.0705 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15292.203 | 0.3815 | 0.0705 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15292.203 | 0.2904 | -0.1034 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15292.203 | 0.2904 | -0.1034 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15292.203 | 0.1548 | -0.4037 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15292.203 | 0.1548 | -0.4037 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15292.203 | 0.0933 | -0.5706 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15292.203 | 0.0933 | -0.5706 | 1.5415 | |
| EFM-192C | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15292.203 | 0.0521 | -0.7060 | 1.5415 |