Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10644.147 | 0.9734 | 0.8798 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10644.147 | 0.9614 | 0.8267 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10644.147 | 1.0310 | 1.1455 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10644.147 | 0.9977 | 0.9893 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10644.147 | 1.0091 | 1.0423 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10644.147 | 0.8341 | 0.3179 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10644.147 | 0.5896 | -0.4064 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10644.147 | 0.0045 | -1.0000 | 0.4349 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10874.147 | 1.0288 | 1.0774 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10874.147 | 1.0291 | 1.0781 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10874.147 | 1.0210 | 1.0564 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10874.147 | 0.9983 | 0.9954 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10874.147 | 1.0423 | 1.1140 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10874.147 | 0.9907 | 0.9751 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10874.147 | 0.9341 | 0.8257 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10874.147 | 0.6725 | 0.1768 | 0.7482 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10874.147 | 0.0628 | -0.9506 | 0.7482 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11851.147 | 0.9406 | 0.9144 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11851.147 | 0.9775 | 0.9678 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11851.147 | 0.9992 | 0.9989 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11851.147 | 0.9429 | 0.9178 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11851.147 | 0.9817 | 0.9738 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11851.147 | 0.9325 | 0.9026 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11851.147 | 0.8608 | 0.7969 | 1.4004 | |
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11851.147 | 0.8273 | 0.7467 | 1.4004 |