Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 7539.087 | 0.2027 | -0.4621 | 1.2155 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7542.086 | 1.0354 | 1.0682 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7542.086 | 0.9900 | 0.9807 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7542.086 | 0.7940 | 0.6013 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7542.086 | 0.5534 | 0.1306 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7542.086 | 0.3682 | -0.2365 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 7542.086 | 0.3108 | -0.3515 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 7542.086 | 0.2878 | -0.3980 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 7542.086 | 0.2245 | -0.5261 | 1.0375 | |
| T47D | HR+ | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 7542.086 | 0.1709 | -0.6357 | 1.0375 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7544.087 | 0.9806 | 0.9668 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7544.087 | 0.9500 | 0.9143 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7544.087 | 1.0122 | 1.0208 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7544.087 | 0.7949 | 0.6441 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7544.087 | 0.5716 | 0.2407 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.267 | uM | 7544.087 | 0.4018 | -0.0817 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 1.33 | uM | 7544.087 | 0.4199 | -0.0464 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 6.67 | uM | 7544.087 | 0.3477 | -0.1883 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 33.3 | uM | 7544.087 | 0.2963 | -0.2919 | 1.1715 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7545.087 | 1.0119 | 1.0210 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7545.087 | 0.9723 | 0.9510 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7545.087 | 0.9401 | 0.8938 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7545.087 | 0.8023 | 0.6465 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7545.087 | 0.4990 | 0.0825 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 0.267 | uM | 7545.087 | 0.3306 | -0.2475 | 1.1323 |