Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10938.147 | 0.9034 | 0.7875 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10938.147 | 0.6507 | 0.2440 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10938.147 | 0.9398 | 0.8674 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10938.147 | 0.9732 | 0.9409 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10938.147 | 0.7415 | 0.4372 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10938.147 | 0.4213 | -0.2305 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12333.147 | 0.8627 | 0.6108 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12333.147 | 0.9280 | 0.7926 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12333.147 | 1.0013 | 1.0039 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12333.147 | 0.9400 | 0.8267 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12333.147 | 0.9179 | 0.7641 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12333.147 | 0.9669 | 0.9037 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12333.147 | 1.0639 | 1.1900 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12333.147 | 0.9820 | 0.9474 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12333.147 | 0.5009 | -0.2737 | 0.6826 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12414.147 | 0.9587 | 0.9266 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12414.147 | 0.9026 | 0.8263 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12414.147 | 0.9388 | 0.8910 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12414.147 | 0.9751 | 0.9558 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12414.147 | 0.9706 | 0.9478 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12414.147 | 0.9467 | 0.9051 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12414.147 | 0.9301 | 0.8755 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12414.147 | 0.7016 | 0.4606 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12414.147 | 0.0964 | -0.7490 | 1.1273 | |
| MX1 | Unknown | Unknown | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10644.147 | 0.9620 | 0.8296 | 0.4349 |