Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14260.189 | 0.9724 | 0.9651 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14260.189 | 0.9724 | 0.9651 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14260.189 | 0.8865 | 0.8540 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14260.189 | 0.8865 | 0.8540 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14260.189 | 0.2679 | -0.1271 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14260.189 | 0.2679 | -0.1271 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14260.189 | 0.0015 | -0.9670 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14260.189 | 0.0015 | -0.9670 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14260.189 | 0.0004 | -0.9845 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14260.189 | 0.0004 | -0.9845 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14260.189 | 1.1907 | 1.2323 | 1.5886 | |
| Hs 578T | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14260.189 | 1.1907 | 1.2323 | 1.5886 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10816.145 | 1.0277 | 1.0716 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10816.145 | 1.0277 | 1.0716 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10816.145 | 1.1372 | 1.3601 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10816.145 | 1.1372 | 1.3601 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10816.145 | 0.9564 | 0.8884 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10816.145 | 0.9564 | 0.8884 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10816.145 | 0.9669 | 0.9152 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10816.145 | 0.9669 | 0.9152 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10816.145 | 1.0105 | 1.0271 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10816.145 | 1.0105 | 1.0271 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10816.145 | 0.0663 | -0.9392 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10816.145 | 0.0663 | -0.9392 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10816.145 | 0.0111 | -0.9939 | 0.7766 |