Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Nelfinavir | 0.0533 | uM | 13062.174 | 0.9663 | 0.9593 | 1.6688 | |||
| SUM229PE | TNBC | - | Nelfinavir | 0.267 | uM | 13062.174 | 0.9803 | 0.9763 | 1.6688 | |||
| SUM229PE | TNBC | - | Nelfinavir | 1.33 | uM | 13062.174 | 0.9616 | 0.9536 | 1.6688 | |||
| SUM229PE | TNBC | - | Nelfinavir | 6.67 | uM | 13062.174 | 0.9844 | 0.9812 | 1.6688 | |||
| SUM229PE | TNBC | - | Nelfinavir | 33.3 | uM | 13062.174 | 0.9008 | 0.8787 | 1.6688 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 12969.174 | 0.9374 | 0.8877 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 12969.174 | 0.9114 | 0.8409 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 12969.174 | 0.8972 | 0.8153 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 12969.174 | 1.0083 | 1.0148 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 12969.174 | 0.9953 | 0.9916 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.267 | uM | 12969.174 | 0.9126 | 0.8430 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 1.33 | uM | 12969.174 | 0.9126 | 0.8430 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 6.67 | uM | 12969.174 | 0.8074 | 0.6521 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 33.3 | uM | 12969.174 | 0.2594 | -0.4010 | 1.1194 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 13570.174 | 0.9677 | 0.8774 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 13570.174 | 0.9667 | 0.8739 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 13570.174 | 0.8994 | 0.6310 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 13570.174 | 1.0576 | 1.2274 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 13570.174 | 1.0114 | 1.0441 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 0.267 | uM | 13570.174 | 1.0059 | 1.0230 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 1.33 | uM | 13570.174 | 0.9421 | 0.7830 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 6.67 | uM | 13570.174 | 1.0162 | 1.0627 | 0.5197 | |||
| SUM52PE | HR+ | Luminal | Nelfinavir | 33.3 | uM | 13570.174 | 0.8209 | 0.3681 | 0.5197 | |||
| T47D | HR+ | Luminal | Nelfinavir | 0.0000853 | uM | 12720.174 | 0.9439 | 0.8842 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 0.000427 | uM | 12720.174 | 0.9312 | 0.8580 | 0.9688 |