Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7454.066 | 0.8570 | 0.7719 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7454.066 | 0.8359 | 0.7377 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7454.066 | 0.8409 | 0.7458 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7454.066 | 0.8121 | 0.6988 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7454.066 | 0.7549 | 0.6042 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7454.066 | 0.7817 | 0.6487 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7454.066 | 0.4207 | 0.0140 | 1.2748 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7455.066 | 0.9858 | 0.9781 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7455.066 | 0.9710 | 0.9552 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7455.066 | 0.9097 | 0.8593 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7455.066 | 1.0507 | 1.0777 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7455.066 | 1.0148 | 1.0227 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7455.066 | 0.8301 | 0.7326 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7455.066 | 0.8139 | 0.7066 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7455.066 | 0.7608 | 0.6201 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7455.066 | 0.0776 | -0.7211 | 1.2976 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7456.066 | 0.9805 | 0.9780 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7456.066 | 1.0467 | 1.0520 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7456.066 | 0.9846 | 0.9826 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7456.066 | 1.0716 | 1.0793 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7456.066 | 1.0196 | 1.0220 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7456.066 | 0.9303 | 0.9204 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7456.066 | 1.0103 | 1.0116 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7456.066 | 0.8389 | 0.8118 | 1.7785 | |
| HCC1954 | HER2amp | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7456.066 | 0.0293 | -0.7251 | 1.7785 |