Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Nelfinavir | 0.00213 | uM | 12720.174 | 0.9534 | 0.9038 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 0.0107 | uM | 12720.174 | 0.9757 | 0.9499 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 0.0533 | uM | 12720.174 | 0.9673 | 0.9325 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 0.267 | uM | 12720.174 | 0.9494 | 0.8956 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 1.33 | uM | 12720.174 | 0.9539 | 0.9048 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 6.67 | uM | 12720.174 | 0.8957 | 0.7851 | 0.9688 | |||
| T47D | HR+ | Luminal | Nelfinavir | 33.3 | uM | 12720.174 | 0.2783 | -0.4660 | 0.9688 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.0000853 | uM | 13070.174 | 0.9897 | 0.9743 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.000427 | uM | 13070.174 | 0.9638 | 0.9099 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.00213 | uM | 13070.174 | 0.9988 | 0.9969 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.0107 | uM | 13070.174 | 1.0161 | 1.0403 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.0533 | uM | 13070.174 | 1.0015 | 1.0038 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 0.267 | uM | 13070.174 | 0.9745 | 0.9364 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 1.33 | uM | 13070.174 | 0.9754 | 0.9386 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 6.67 | uM | 13070.174 | 1.0210 | 1.0527 | 0.7993 | |||
| T47DKBLUC | Unknown | Unknown | Nelfinavir | 33.3 | uM | 13070.174 | 1.0229 | 1.0576 | 0.7993 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.0000853 | uM | 13078.174 | 0.9839 | 0.9488 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.000427 | uM | 13078.174 | 0.9627 | 0.8819 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.00213 | uM | 13078.174 | 0.9744 | 0.9184 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.0107 | uM | 13078.174 | 1.0120 | 1.0386 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.0533 | uM | 13078.174 | 0.9867 | 0.9575 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 0.267 | uM | 13078.174 | 0.9804 | 0.9377 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 1.33 | uM | 13078.174 | 0.9638 | 0.8852 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 6.67 | uM | 13078.174 | 0.9973 | 0.9914 | 0.6238 | |||
| UACC-812 | HER2amp | Luminal | Nelfinavir | 33.3 | uM | 13078.174 | 1.0221 | 1.0714 | 0.6238 |