Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10816.145 | 0.0111 | -0.9939 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10816.145 | 0.0159 | -0.9903 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10816.145 | 0.0159 | -0.9903 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10816.145 | 0.0041 | -0.9983 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10816.145 | 0.0041 | -0.9983 | 0.7766 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12319.17 | 0.8598 | 0.4487 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12319.17 | 0.8598 | 0.4487 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12319.17 | 1.0253 | 1.1095 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12319.17 | 1.0253 | 1.1095 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12319.17 | 0.9464 | 0.7780 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12319.17 | 0.9464 | 0.7780 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12319.17 | 1.2285 | 2.1033 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12319.17 | 1.2285 | 2.1033 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12319.17 | 1.1007 | 1.4549 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12319.17 | 1.1007 | 1.4549 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12319.17 | 0.1896 | -0.9426 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12319.17 | 0.1896 | -0.9426 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12319.17 | 0.0158 | -0.9997 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12319.17 | 0.0158 | -0.9997 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12319.17 | 0.0163 | -0.9997 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12319.17 | 0.0163 | -0.9997 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12319.17 | 0.0083 | -0.9999 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12319.17 | 0.0083 | -0.9999 | 0.4684 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14134.189 | 0.9863 | 0.9900 | 2.7572 | |
| LY2 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14134.189 | 0.9863 | 0.9900 | 2.7572 |